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Efficacy of copper oxide nanoparticles using Piper longum and Piper betle



Tejitha Ambati, Vamshi Nizampuram, Sahana Selvaganesh, S Rajeshkumar & Thiyaneswaran Nesappan



Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science, Chennai, Tamilnadu, India; *Corresponding author



Sahana Selvaganesh E-mail: sahanas.sdc@saveetha.com; Phone: +91 9444964693

Tejitha Ambati E-mail: atejithareddy@gmail.com

Vamshi Nizampuram E-mail: vamshi.nizampuram@gmail.com

S Rajeshkumar E-mail: rajeshkumars.sdc@saveetha.com

Thiyaneswaran Nesappan E-mail: drthiyan@gmail.com


Article Type

Research Article



Received September 1, 2023; Revised September 30, 2023; Accepted September 30, 2023, Published September 30, 2023



It is of interest to evaluate the antibacterial, anti-inflammatory, and antioxidant effects of copper nanoparticles synthesized using Piper longum and Piper betle. The copper nanoparticles were characterized using various techniques and found to have a diameter between 30 and 90 nm. The nanoparticles exhibited significant antibacterial activity against E. faecalis, S. aureus, C. albicans, and S. Mutans, comparable to gold standards. They also demonstrated anti-inflammatory effects similar to the gold standard values. Furthermore, the copper nanoparticles displayed antioxidant capabilities, with maximum inhibition of 85.16% at 50 g/ml and a minimum inhibition of 50.62% at 10 g/ml. Overall, the study suggests that Piper longum and Piper betle mediated copper nanoparticles possess promising antibacterial, anti-inflammatory, and antioxidant properties, indicating their potential use in various applications.



Efficacy, copper oxide, nanoparticles, Piper longum and Piper betle



Ambati et al. Bioinformation 19(9): 964-970 (2023)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.