Title

Diabetic pulmonary microangiopathy and its association with glycated haemoglobin and other diabetic complications

Authors

M Lokesh, S.V. Srinivasa & Mani Mohan Reddy*

Affiliation

Department of General Medicine, Sri Devraj URS Academy of Higher Education And Research, Kolar, Karnataka, India; *Corresponding author

Email

M Lokesh - E-mail: lokeshtriambik@gmail.com
SV Srinivasa - E-mail: drsrinivasa.dvl@sduaher.ac.in
Mani Mohan Reddy - E-mail: manimohanhp@gmail.com

Article Type

Research Article

Date

Received July 1, 2025; Revised July 31, 2025; Accepted July 31, 2025, Published July 31, 2025

Abstract

Diabetes mellitus is a systemic disease now recognized to affect the lungs through microangiopathy. This cross-sectional study assessed pulmonary function via spirometry in 132 diabetics and 132 controls. Diabetics showed significantly reduced FVC, FEV1 and PEFR, consistent with a restrictive pattern. Poor glycemic control correlated strongly with reduced lung function, while disease duration did not. Spirometry findings also correlated with albuminuria and retinopathy, supporting early screening utility.

Keywords

Type 2 diabetes mellitus; pulmonary function tests; spirometry; glycated hemoglobin (HbA1C); albuminuria; diabetic retinopathy; diabetic nephropathy; restrictive lung disease

Citation

Lokesh et al. Bioinformation 21(7): 2186-2190 (2025)

Edited by

A Prashanth

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.