Title

Sealing efficacy of titanium-doped versus conventional MTA in access perforation repair: An in vitro study

Authors

Sneha A Patil¹*, Shamurailatpam Priyadarshini², Rajeswari Putchala³, Vankala Gautam³, Smita Durga Dutta⁴, Heena Dixit Tiwari⁵ & Rahul Tiwari⁶

Affiliation

¹Department of Conservative Dentistry and Endodontics, KLE VK Institute of dental sciences, KLE Academy of Higher Education and Research, Belagavi, Karnataka, India; ²Department of Conservative Dentistry and Endodontics, Dental College, RIMS, Imphal, Manipur, India; ³Department of Conservative & Endodontics, ST. Joseph's Dental College, Duggirala, NTR University of health sciences andhra Pradesh, India; ⁴Department of Conservative Dental Sciences and Endodontics, College of Dentistry, Qassim University, Kingdom of Saudi Arabia; ⁵Commisionerate of Health and Family Welfare, Government of Telangana, Hyderabad, India; ⁶Department of Oral and Maxillofacial Surgery, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India; *Corresponding author

Email

Sneha A Patil - E-mail: drsnehapatil9@gmail.com

Shamurailatpam Priyadarshini - E-mail: dr26priya@gmail.com
Rajeswari Putchala - E-mail: dr.rajijoy@gmail.com
Vankala Gautam - E-mail: vankala.gautam@gmail.com
Smita Durga Dutta - E-mail: smita_d_dutta@yahoo.com
Heena Dixit Tiwari - E-mail: drheenatiwari@gmail.com
Rahul Tiwari - E-mail: drrahulvctiwari@gmail.com

Article Type

Research Article

Date

Received August 1, 2025; Revised August 31, 2025; Accepted August 31, 2025, Published August 31, 2025

Abstract

Mineral trioxide aggregate (MTA) is known for good sealing and also for its biocompatibility. However, limitations such as extended setting time and potential leakage persist. Therefore, it is of interest to compare the sealing efficacy of titanium-doped MTA and conventional MTA in the repair of access perforations using in vitro dye penetration model fourty extracted human mandibular premolars were used. Titanium-doped MTA showed significantly less dye penetration (mean 0.92 mm) compared to conventional MTA (mean 1.46 mm) (p = 0.001), indicating superior sealing efficacy. Thus, Titanium-doped MTA demonstrates better sealing capability than conventional MTA and may serve as an improved material for perforation repair.

Keywords

Mineral trioxide aggregate (MTA), titanium-doped MTA, access perforation, microleakage, endodontic repair

Citation

Patil et al. Bioinformation 21(8): 2481-2484 (2025)

Edited by

Akshaya Ojha

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.